The South Carolina Conference has been instrumental in beginning many “firsts” in the Pentecostal Holiness Church which have been adopted and has become a part of the International Pentecostal Holiness Church today. Among those include what is known today as the Global Outreach Offering, having its beginning under then Conference Superintendent, Rev. T. O. Evans back in 1952. The Ministers Wives Fellowship had its beginning in the South Carolina Conference as well as the Mobile Feeding Kitchen and Disaster Relief USA.

The South Carolina Conference has made a dynamic impact on the International Pentecostal Holiness Church and the International Pentecostal Holiness Church has impacted the South Carolina Conference.